Monitor hematocrit prior to initiation at 3 6 months after starting therapy then annually. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away. Nausea vomiting headache dizziness hair loss increased hair growth trouble sleeping changes in sexual desire redness swelling itching burning hardening of the skin where the patch is worn change in skin color breast swelling or tenderness.